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https://www.facebook.com/people/SMC-Laboratories-Inc/100063634083949/
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              <p class="mv-txt01">NEWS RELEASE</p>
              <p class="mv-ttl01">【Breaking News!】 First MASH treatment approved by FDA</p>
              <p class="mv-ttl02"></p><p>On March 14th, The United States Food and Drug Administration (FDA) announced their approval of Rezdiffra (res…</p>
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              <p class="mv-ttl01">SMC will be exhibiting at The 110th General Meeting of the Japanese Society of Gastroenterology</p>
              <p class="mv-ttl02"></p><p>We are pleased to announce that SMC Laboratories will be exhibiting at The 110th General Meeting of the Japane…</p>
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                            <p class="mv-ttl01">Cell metab.,</p>
              <p class="mv-ttl02">“MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity” (Cell Metab., DOI: 10.1016/j.cmet.2022.10.007., 2022)</p>
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              <p class="mv-ttl01">STAM™ model</p>
              <p class="mv-ttl02">Our STAM™ model is a model that recapitulates the same disease progression as human MASH/HCC.</p>
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            <p class="desc">In addition to the liver disease area that we focus on, we also provide non-clinical pharmacology studies for various other disease areas.</p>
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            <h3 class="ttl">Mechanism of action</h3>
            <p class="desc">The STAM™ mouse is our in-house developed model. It  is a MASH-HCC model with a diabetes background. So far, we have over 15 MOA categories and more than 270 target molecules of test substances that we have evaluated using STAM™ mice.</p>
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            <p class="desc">Results of non-clinical pharmacology studies by our company have been presented at many major academic conferences in the United States and Europe, such as DDW, AASLD, EASL, ADA, or AACR. It has also been published in journals such as PNAS, Hepatology, or Cell metabolism.</p>
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            <p class="desc01">We are contributing to the world through providing cutting-edge non-clinical pharmacology studies with our unique patented technology, the STAM™ mouse. In order to develop a new drug, it is important to be able to accurately measure the effectiveness of the drug at the non-clinical trial stage. The STAM™ mouse, a model that more accurately reflects human pathology, plays a major role for this purpose.</p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Pitfalls of [ disease model mice ] that researchers unknowingly fall into.</h3></div>
                        <p class="item-desc"></p><p>In order to evaluate your compound, rather than using a general pulmonary fibrosis model that does not match y…</p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">| A must for IPF researchers! | Suggestions for the best disease model for your research</h3></div>
                        <p class="item-desc"></p><p>If you are considering a drug efficacy study using a mouse model of lung fibrosis, you should use a model that…</p>
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            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/a-must-for-ipf-researchers-suggestions-for-the-best-disease-model-for-your-research/"><span class="txt">READ MORE</span></a></p>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">【Hot data】 Resmetirom (MGL-3196) evaluation data available in STAM<sup>TM</sup> model</h3></div>
                        <p class="item-cats"><span class="cat">MASH</span><span class="cat">Resmetirom</span><span class="cat">STAM</span></p>
                        <p class="item-desc"></p><p>As you may already know, the United States Food and Drug Administration (FDA) announced the approval of Rezdif…</p>
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            <p class="item-date">2024.03.21</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">What is the best non-clinical liver cancer model with 100% cancer incidence rate and suitable for liver cancer assessment?</h3></div>
                        <p class="item-desc"></p><p>If you are considering a drug evaluation study for liver cancer using a mouse model, our STAMTM-HCC/IO+ model …</p>
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            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/what-is-the-best-non-clinical-liver-cancer-model-with-100-cancer-incidence-rate-and-suitable-for-liver-cancer-assessment/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.19</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">[ Breaking News! ] First MASH treatment approved by FDA</h3></div>
                        <p class="item-desc"></p><p>On March 14th, industry-altering news was published. Do you know already what we are talking about? The United…</p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">[Existing compounds] that have advanced to clinical trials will accelerate the launch of your drugs.</h3></div>
                        <p class="item-desc"></p><p>If you are planning to launch your therapeutic drug, you should select disease mouse models that have shown ac…</p>
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            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/existing-compounds-that-have-advanced-to-clinical-trials-will-accelerate-the-launch-of-your-drugs/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Pitfalls of [ disease model mice ] that researchers unknowingly fall into.</h3></div>
                        <p class="item-desc"></p><p>In order to evaluate your compound, rather than using a general pulmonary fibrosis model that does not match y…</p>
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            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/pitfalls-of-disease-model-mice-that-researchers-unknowingly-fall-into/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">| A must for IPF researchers! | Suggestions for the best disease model for your research</h3></div>
                        <p class="item-desc"></p><p>If you are considering a drug efficacy study using a mouse model of lung fibrosis, you should use a model that…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/a-must-for-ipf-researchers-suggestions-for-the-best-disease-model-for-your-research/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.04.08</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">【Hot data】 Resmetirom (MGL-3196) evaluation data available in STAM<sup>TM</sup> model</h3></div>
                        <p class="item-cats"><span class="cat">MASH</span><span class="cat">Resmetirom</span><span class="cat">STAM</span></p>
                        <p class="item-desc"></p><p>As you may already know, the United States Food and Drug Administration (FDA) announced the approval of Rezdif…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/%e3%80%90hot-data%e3%80%91-resmetirom-mgl-3196-evaluation-data-available-in-stam-model/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.21</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">What is the best non-clinical liver cancer model with 100% cancer incidence rate and suitable for liver cancer assessment?</h3></div>
                        <p class="item-desc"></p><p>If you are considering a drug evaluation study for liver cancer using a mouse model, our STAMTM-HCC/IO+ model …</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/what-is-the-best-non-clinical-liver-cancer-model-with-100-cancer-incidence-rate-and-suitable-for-liver-cancer-assessment/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.19</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">[ Breaking News! ] First MASH treatment approved by FDA</h3></div>
                        <p class="item-desc"></p><p>On March 14th, industry-altering news was published. Do you know already what we are talking about? The United…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/breaking-news-first-mash-treatment-approved-by-fda/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">[Existing compounds] that have advanced to clinical trials will accelerate the launch of your drugs.</h3></div>
                        <p class="item-desc"></p><p>If you are planning to launch your therapeutic drug, you should select disease mouse models that have shown ac…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/existing-compounds-that-have-advanced-to-clinical-trials-will-accelerate-the-launch-of-your-drugs/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Pitfalls of [ disease model mice ] that researchers unknowingly fall into.</h3></div>
                        <p class="item-desc"></p><p>In order to evaluate your compound, rather than using a general pulmonary fibrosis model that does not match y…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/pitfalls-of-disease-model-mice-that-researchers-unknowingly-fall-into/"><span class="txt">READ MORE</span></a></p>
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            <p class="item-date">2024.03.15</p>
            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">| A must for IPF researchers! | Suggestions for the best disease model for your research</h3></div>
                        <p class="item-desc"></p><p>If you are considering a drug efficacy study using a mouse model of lung fibrosis, you should use a model that…</p>
<p></p>
            <p class="item-btn"><a class="c-btn01 smaler01" href="https://www.smccro-lab.com/column/a-must-for-ipf-researchers-suggestions-for-the-best-disease-model-for-your-research/"><span class="txt">READ MORE</span></a></p>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Case study: Study published in Clinical and Translational Science on the effects of adiponectin-derived peptide ALY688 in MASH/liver fibrosis of STAM model.</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Case study: Study published in Nature Biotechnology on the effects of TNIK inhibitor in lung and kidney fibrosis models.</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Case study: Study published in Clinical and Translational Science on the effects of adiponectin-derived peptide ALY688 in MASH/liver fibrosis of STAM model.</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Case study: Study published in Nature Biotechnology on the effects of TNIK inhibitor in lung and kidney fibrosis models.</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Preclinical HCC study with positive control, Lenvatinib</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Enhance Research with Our Updated Model Lineup</h3></div>
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            <div class="item-ttl js-height" style="height: 97.1719px;"><h3 class="ttl">Results of Resmetirom fibrosis targeting study using STAM™ model</h3></div>
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